Cranial extramedullary hematopoiesis with pancreatic secondary hemochromatosis in a beta thalassemia patient: A case report

Thalassemia is one of the most worrying hemolytic disorder with wide range evolving clinical alterations based on type, severity affected hematopoietic mechanisms and repeated transfusions to correct underlying anemia.We present a 13 year old female patient diagnosed thalassemia major showing features cranial extra medullary hematopoiesis severe intracranial infections in form cerebellar abscess otomastoiditis extending adjacent sinus venouses, Iron deposition liver & pancreas incidental findings uncomplicated horse shoe kidney.Extra catch up mechanism at failing hematopoeising keep check hemoglobin levels without causing much physiological imbalance.EMH usually affects visceral structures like liver, spleen lymph nodes thorax. Less commonly pleura, lungs, GIT, breast, skin, kidneys, adrenals rarely cranium structures. Here, we rare presentations EMH background infection.